Our experience of the use of thalidomide in the steroid-dependent severe erythema nodosum leprosum.

Sir, Severe, chronic, recurrent erythema nodosum leprosum (ENL) is a serious problem. Patients are in need of effective and safe treatment because there is a danger of steroid dependence. Thalidomide has been shown to be highly effective in the treatment of refractory ENLs.[1] A number of dosage regimens of thalidomide, an expensive drug, have been tried.[1-3] We describe our experience of the use of a new dosage regimen of thalidomide in the management of steroiddependent severe ENLs.